Health experts have tended to shy away from explicitly promoting e-cigarettes.
But the government campaign during October will feature vaping in its TV adverts for the first time.
It comes after e-cigarettes proved the most popular tool for quitting during last year’s campaign.
Some 53% of people used them, helping push the numbers of people taking part in Stoptober since its launch in 2012 to over 1.5 million.
E-cigarettes are not yet officially prescribed on the NHS.
However, doctors and other health professionals are encouraged to advise smokers who want to use them that they are a better alternative to smoking.
New draft guidance from the National Institute for Health and Care Excellence (NICE) does not list e-cigarettes as a recommendation to help people quit, but says patients should be told some smokers have found them helpful when they want to give up.
Nice advises that patients should be told that there “is currently little evidence on the long-term benefits or harms of these products”.
Government experts have been encouraged by newly released research suggesting record numbers of attempts to give up are proving successful.
University College London researchers found 20% of attempts were successful in the first six months of 2017, compared with an average of 16% over the previous 10 years.
A successful attempt was judged to be one where the person had tried to stop smoking in the past year and was still abstaining at the time of the survey.
The biggest rise in successful attempts to quit was among people from poorer backgrounds, who have traditionally been the least likely to give up.
Deputy chief medical officer Prof Gina Radford said e-cigarettes were playing an important role and as they had “95% less harmful products” in them than cigarettes it was only right that they were promoted during Stoptober.
But she also said there were a number of other factors that were proving effective in reducing smoking rates, including restrictions that have been brought in such as standardised packaging and bans on displays in shops.